Congratulations to Dr. Aidan Moriarty!
Aidan defended her thesis titled “Establishment of a Highly Prognostic Hypoxic Memory Metagene Signature in Luminal Breast Cancer” on November 25th, 2024.
November 2024
Happy Halloween!
We celebrated Halloween and volunteered at UMB’s community trick or treat event!
October 2024
Pool party!
The Yu lab got together to celebrate our Cancer Research publication and the end of the summer!
September 2024
Congrats to Anu for passing her qualifying exam and advancing to PhD candidacy!
September 2024
Cancer Research Publication
Hypoxic Memory Mediates Prolonged Tumor Intrinsic Type I Interferon Suppression to Promote Breast Cancer Progression
DOI: https://doi.org/10.1158/0008-5472.CAN-23-2028
Iriando O, Mecenas D, Li Y, Chin C, Thomas A, Moriarty A, Marker R, Wang YJ, Hendrick H, Amzaleg Y, Ortiz V, MacKay M, Dickerson A, Lee G, Harotoonian S, Benayoun B, Smith A, Mason C, Roussos Torres E, Klotz R, Yu M.July 2024
Welcome to the lab, Yamini Nagidi!
July 2024
Mammary Gland Biology Gordon Research Conference in Italy
Remi, Aidan, and Min attended.
June 2024
Farewell to Jess!
Our lab tech, Jess is off to medical school at the University of Illinois, Chicago. We celebrated her over brunch at Gunther and Co. We will miss you, Jess!
Jess’ goodbye brunch 
Min and Jess May 2024
Congratulations to Rebecca for passing her qualifying exam and advancing to candidacy!
May 2024
Welcome to the lab, JiaJia Gu!
April 2024
Advanced Science Publication
Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity
Kang DS*, Moriarty A*, Wang YJ, Thomas A, Hao J, Unger BA, Klotz R, Ahmmed S, Amzaleg Y, Martin S, Vanapalli S, Xu K, Smith A, Shen K, Yu M.
February 2024
Congratulations to Jess for getting into medical school!
February 2024
Welcome to the lab Tamasa De!
December 2023
San Antonio Breast Cancer Symposium (SABCS) Conference
Aidan and Min attended.
December 2023
Congratulations Dr. Remi V. Klotz!
2023 Celselect Research Grant recipient
Grant Research Title: Uncovering the molecular vulnerabilities of circulating tumor cells
To date, no studies have definitively identified the underlying molecular mechanisms that allow tumor cells to penetrate blood vessel walls and enter circulation. Understanding the molecular mechanisms of intravasation is crucial for the development of therapeutic strategies to prevent metastasis. In our study, we will conduct a genome-wide CRISPR activation (CRISPRa) screen in a syngeneic mouse tumor model in combination with Genesis Cell Isolation System and Celselect Slides™ for the isolation of rare cells to uncover genetic determinants of cancer cell intravasation and survival in the bloodstream. Relative enrichment for sgRNA from isolated mouse CTCs derived from two mouse breast cancer cell lines transplanted in immunocompetent mice will be determined by comparing results to the transduced tumor cells before injection and corresponding primary tumor. Finally, to assess the clinical relevance of the top hits, protein expression analysis of these candidates in our established patient-derived CTC lines and CTCs freshly isolated from patients (10-20 patients) will be performed by direct immunolabeling on Celselect Slides™.
November 21st, 2023
Happy Thanksgiving from the Min Yu lab!
November 19th 2023
Happy Halloween from the Min Yu Lab!
October 31st, 2023
Welcome to the lab Anu Sunkara!
October 2023
Advances in Circulating Tumor Cells (ACTC) Conference in Skiathos Island, Greece
Aidan presented a poster!
September 2023
Welcome to the lab Rebecca Marker!
August 2023
Cancer Publication
An Image-Based Identification of Aggressive Breast Cancer Circulating Tumor Cell Subtypes
Kamal M, Wang YJ, Plummer S, Dickerson A, Yu M.
May 2023
Min Yu lab moves to University of Maryland, Baltimore!
January 2023
-
Subscribe
Subscribed
Already have a WordPress.com account? Log in now.
minyulab.org 